DATA & SOFTWARE
DATA & SOFTWARE
SOFTWARE
RERconverge on GitHub
RERconverge is an R package that estimates the correlation between relative evolutionary rates of genes and the evolution of a convergent binary or continuous trait across a phylogeny.
RERconverge Walk-Throughs
Full step-by-step instructions (pdf or html) on how to identify genetic elements correlated with the convergent evolution of your trait of interest.
Evolutionary Rate Covariation (ERC) on GitHub
ERC measures correlated rates across a phylogeny, allowing for extraction of genes with similar evolutionary histories. High ERC values are typically observed between genes participating in a common pathway or that otherwise share functionality, and so they are useful to predict new functional and gene-gene interactions..
ERC Analysis Webserver
ERC analysis tools operating on an older set of ERC results in mammals, Drosophila, and yeasts.
DATASETS AND REPOSITORIES ACCOMPANYING PAPERS
2022 Lucas et al. “Highly Dynamic Gene Family Evolution Suggests Changing Roles for PON Genes Within Metazoa”
Multiple sequence alignments and phylogenetic trees. Download: aln_trees.zip
2019 Raza et al. PLOS Genetics
Data in Dryad repository from: Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila
2018 Meyer et al. Science.
This repository contains scripts associated with a genome-wide screen for convergent loss of gene function in marine mammals.
2012 Clark, Alani, Aquadro. Genome Research
ERC Yeast Dataset 2012